A two-barrier compartment model for volume flow across amphibian skin.

A Two-Barrier Compartment Model for Volume Flow across Amphibian Skin Running title: volume flow across amphibian skin

Mechanism of L-glucose, raffinose, and inulin transport across intact blood-brain barriers.

Brain capillary permeability-surface area products (PS) of hydrophilic solutes were evaluated in terms of a conventional two-compartment model. In rats whose blood-brain barrier (BBB) was presumed to be intact, metabolically inert carbohydrates with different molecular weights were injected in pairs to elucidate whether their transfer into the brain proceeds by diffusion through water- or lipid...

Effects of temporal sampling, glucose metabolic rates, and disruptions of the blood-brain barrier on the FDG model with and without a vascular compartment: studies in human brain tumors with PET.

The addition of a cerebral blood volume (CBV) compartment in the [18F]2-fluoro-2-deoxy-D-glucose (FDG) model produces estimates of local CBV simultaneously with glucose metabolic rates when kinetic FDG studies are performed. We investigated the influence of this term upon CMRglc values in a series of brain tumor patients and found that significant overestimations of CMRglc are possible if the e...

Localizing transepithelial conductive pathways using a vibrating voltage probe.

A model simulation of the electrical field distribution for the voltage-activated C1- current across amphibian skin has been carried out for two potential pathways, i.e. transcellularly, through the mitochondria-rich cells (MRCs), or paracellularly, across the tight junctions (TJs) between the outermost living cell layer. The calculations are based on the mean density of MRCs and the typical di...

Effect of Elasticity Parameter on Viscoelastic Fluid in Pipe Flow Using Extended Pom-Pom Model

In this study prediction of the steady-state flow of branched polymer melts in pipe geometry with finite volume method is presented. Our analysis in this study revealed that;for normal-stress tqq , the XPP model can predict this tensor unlike the other viscoelastic models such as PTT or Gieskus which can not predict tqq...